Banca de QUALIFICAÇÃO: MARIA GISLAINE PEREIRA
Uma banca de QUALIFICAÇÃO de DOUTORADO foi cadastrada pelo programa.DISCENTE: MARIA GISLAINE PEREIRA
DATA : 29/01/2024
LOCAL: VIDEOCONFERÊNCIA
TÍTULO:
Evidences of radioresistance in a population of Drosophila melanogaster from Cerro Corá, semiarid region of Brazil, a place with high background radiation
PALAVRAS-CHAVES:
Radon. Caatinga. Deleterious effects. Model organism.
PÁGINAS: 20
RESUMO:
Ionizing radiation can cause profound deleterious effects on cells, depending on the dose and exposure time, because it is capable of penetrating the living organisms, where it induces the ionization of both organic and inorganic compounds. However, studies demonstrate the relevance of adaptive intrinsic genetic and epigenetic characteristics to repair the damages and maintain the integrity of DNA. The Northeast region of Brazil is an ideal place for studies on this topic, in its environments rich in natural radioactivity that comes from rocky outcrops rich in Uranium and Thorium. This work highlights the presence of radioresistance in a natural population of Drosophila melanogaster resident in Cerro Corá (CC-res), a small, sparsely urbanized municipality with high levels of Radon (> 2800 Bq.m-3). The genotoxic effects associated with natural radiation and gamma radiation induced by 60Co (10, 30, 50 and 70 Gray), were evaluated by the Comet assay in CC-res, after seven and 13 months of laboratory cultivation, and in D. melanogaster Oregon-R (group control). The results show low rates of damage to CC-res larvae and adults (radioresistance), regardless of the climatic season of exposure (dry or rainy) or the time of cultivation in the laboratory. Likewise, CC-res was more tolerant to the effects of gamma radiation and only Oregon-R presented high damages with a dose-response effect. The results open perspectives for new studies of in vivo exposure of wildlife in order to correlate radiation dose with known radiological effects.
MEMBROS DA BANCA:
Presidente - 1124755 - ANDRE MORGADO ESTEVES
Externo ao Programa - 1547195 - CRISTIANO APARECIDO CHAGAS - nullInterna - 2352978 - LUCIANA IANNUZZI
Interno - 1551332 - PAULO SERGIO MARTINS DE CARVALHO