OBTAINING A BIMODAL SYSTEM IN POROUS BETA TITANIUM DISCS WITH POTENTIAL CAPACITY FOR BACTERIAL INHIBITION AND CELL GROWTH INDUCTION
Metal alloy; surface modification; Biocompatibility.
Biomedical alloys are notable materials in the biomedical sector today. However, they have limitations in meeting the clinical requirements in the production of implants that guarantee a successful implant. Due to structural incompatibility, obtaining a uniform and homogeneous surface becomes a factor that generates rejection of some type of bone defect. The modification of the physicochemical surface in structures with densities close to the bone can be an effective way to improve their bio-functionality, such as the fabrication of porous structures functionalized with nano-type materials that can have an inhibition effect on the formation of undesirable structures such as the formation of biofilms on the surface of the implants. All these causing failures in the oste-inductive process and millions of deaths, which is why its treatment is a constant challenge in the biomedical and economic sector, where threatening figures of 10 million deaths are expected by 2050, causing millions of dollars in expenses. The main objective of this work is to emphasize the importance of physicochemical modification of the surface of porous titanium metal alloys. In this work, we will analyze the impact of functionalization strategies on TNZT structures with pore sizes between 100-200, 355-500μm and, non-porous with metallic NpsAg by using nonconventional hydroxylation pretreatments in beta alloys. Below, we present the basis and applications of some modifications traditionally and signaling processes rarely used in this type of metal such as TNZT. It also reveals the importance of searching for strategies in materials that improve the performance of physicochemical modifications at the surface level in porous materials, impacting on the improvement of the bio-functionality of metal alloys. Future studies may focus on the development of syntheses of materials functionalized with other types of nanostructures, such as magnetic particles, which lead to the discovery of new applications in the biomedical sector.