Banca de QUALIFICAÇÃO: TAMIRES DA SILVA LIMA

Uma banca de QUALIFICAÇÃO de DOUTORADO foi cadastrada pelo programa.
STUDENT : TAMIRES DA SILVA LIMA
DATE: 31/01/2023
LOCAL: Laboratório 4 do PPG Ciência de Materiais
TITLE:
KEY WORDS:

photopolymerizable nanocomposites; 3D printing; self-decontaminating materials; antiviral activity.

PAGES: 70
BIG AREA: Outra
AREA: Multidisciplinar
SUMMARY:

The development of nanocomposites with self-decontaminating properties has been a key factor for applications in materials that seek to inhibit the growth of microorganisms or viral inactivation. With the emergence of new viruses and bacteria resistant to drugs, the incidence of contamination of materials in common use through contact with contaminated surfaces, considered as fomites, has been a secondary route of virus propagation that presents a high level of transmissibility. The present study proposes the development of a new self-decontaminating material based on nanoparticles of copper, copper oxide and hybrid phase, incorporated into photopolymerizable resins, for the production of printable nanocomposites with potential antiviral activity, acting in the inhibition and propagation of viruses, in especially SARS-Cov- 2, combined with bioinspiration, allowing the exploration of different hierarchical structures through 3D printing technology. This work describes the synthesis and characterization of nanoparticles of copper (CuNP) and copper oxide (CuONP) by two methodologies (chemical and mechanochemical reduction) and preliminary tests of a first produced nanocomposite. To this end, our LandFoton research group (DQF-UFPE) developed a DPL Photon S 3D printing system to optimize the material printing process. Techniques of homogenization of nanoparticles in resin were studied and characterizations of the material were carried out. UVvis, FTIR, XRD and SEM analyzes showed the efficiency of the synthesis approaches in obtaining nanoparticles, with average sizes of 18.3 nm (CuNP) and 8.3 nm (CuONP). The preliminary results regarding the nanocomposite with CuNP showed that there is a good dispersion between the phases, guaranteeing stability and the cytotoxic assays provided a direction for the most suitable type of resin for the production and optimization of the next nanocomposites that will be produced.

COMMITTEE MEMBERS:
Interno - 1301657 - ANDRE GALEMBECK
Interna - 1356402 - CAROLINA LIPPARELLI MORELLI
Presidente - 3100969 - NATHALIA BEZERRA DE LIMA