Banca de QUALIFICAÇÃO: KAMILLA VERONIKA RODRIGUES DE ANDRADE SILVA

Uma banca de QUALIFICAÇÃO de DOUTORADO foi cadastrada pelo programa.
STUDENT : KAMILLA VERONIKA RODRIGUES DE ANDRADE SILVA
DATE: 20/09/2022
LOCAL: Programa de Pós-Graduação em Ciência de Materiais
TITLE:

BIOFUNCTIONALIZATION OF POROUS TITANIUM SURFACE FROM THE USE OF TANIN AND TERPHENOL - D FOR BIOMEDICAL APPLICATIONS

KEY WORDS:

biofunctionalization; porous titanium; bone implant; magnetostriction; tannin.

PAGES: 64
BIG AREA: Outra
AREA: Multidisciplinar
SUMMARY:

Prostheses can be used to replace, mimic, or repair parts of bone tissue that have been lost due to systemic disease and/or injury. Titanium and its alloys are the widely studied and used materials in the application of this type of implant due to their mechanical characteristics, corrosion resistance, and biocompatibility. However, despite its high quality, it is estimated that in the first five years after implantation there is about 10% failure due to problems with osseointegration, resulting in an additional cost of USD 100,000 per patient. Several recent works have been looking for different solutions to reduce problems related to bone implants due to osseointegration. Part of these solutions involves biofunctionalization of the titanium surface. In our studies we will focus on the application of condensed tannin extracted from jurema preta (Mimosa tenuiflora) and angico Vermelho (Anadenanthera macrocarpa), which is traditionally exploited for tannin extraction in northeastern Brazil. The choice of this material is due to its antibacterial potential. At first, the physicochemical characterization of the condensed tannin was carried out, using FTIR and UV-Vis techniques, and later measurements of NMR and TG will be carried out. Once characterized, this material will be deposited on the porous titanium substrate and its antibacterial potential will be evaluated. Another solution suggested by our studies involves the use of materials that have magnetostrictive characteristics such as Terfenol-D (Tb0.3Dy0.7Fe2), we suggest the biofunctionalization of the implanted surface with previous deposition of this magnetostrictive material. Part of this work will be carried out at the University of Seville, from November 2022 to May 2023.

BANKING MEMBERS:
Externo à Instituição - JAMES PIERRE MUIR
Externa à Instituição - Denise Granato Chung
Externo à Instituição - RAMON RAUDEL PENA GARCIA - UFRPE