Banca de DEFESA: RHODIVAM LUCAS MENDES FEITOSA

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : RHODIVAM LUCAS MENDES FEITOSA
DATE: 07/08/2023
TIME: 08:30
LOCAL: Programa de Pós-Graduação em Ciência de Materiais
TITLE:

Thermoresponsive polymeric films with antimicrobial property.

KEY WORDS:

Poly (n-vinylcaprolactam), PNVCL, blend, thermoresponsive polymers, antimicrobial activity, characterization, cinnamon bark essential oil.

PAGES: 107
BIG AREA: Outra
AREA: Multidisciplinar
SUMMARY:

The thermoresponsive polymers are macromolecules capable of reversibly changing their characteristics with temperature variation. This uniqueness makes these materials useful in a wide range of applications such as controlled release of molecules (such as drugs), dressings, scaffolds, tissue engineering and sensors. Poly(N-vinylcaprolactam), PNVCL, is a thermoresponsive and biocompatible polymer whose hydrophilic/hydrophobic transition temperature depends on the molar mass. However, this material does not have good mechanical properties. Poly(butylene adipate co-terephthalate) (PBAT) is a flexible and biocompatible polymer. The production of blends is an interesting route to improve properties by joining different polymers. Cinnamon bark essential oil (CEO) has antimicrobial characteristics and can be used as an additive to polymers to impart this property. In the present work, PNVCL was synthesized by two different routes, one using 3-mercaptopropionic acid (MPA) as chain transfer agent and the other without MPA. PNVCL films were made by casting method. Then, a blend of the thermoresponsive polymer with PBAT was produced by casting in order to improve the mechanical properties. In addition, CEO was added to the polymeric films produced to form potential materials with antimicrobial properties. The obtained materials were characterized by infrared spectroscopy, nuclear magnetic resonance, X-ray fluorescence, X-ray energy dispersive (EDS), differential scanning calorimetry, thermogravimetry, viscosimetry, gel permeation chromatography, cloud point, turbidity test of films, relaxometry, contact angle, scanning electron microscopy, mechanical dynamic analysis, antimicrobial analysis, cytotoxicity. The polymers were obtained by the performed syntheses. There was also success in the formation of polymeric films by casting. The different characterization techniques confirmed the production of thermoresponsive polymers. There was the formation of a partially miscible blend and the addition of essential oil conferred good antimicrobial properties to the materials against Gram-negative and Grampositive bacteria tested. The present research contributes to the dissemination of knowledge about the thermoresponsive polymer PNVCL, and the production of intelligent materials with antimicrobial properties.

COMMITTEE MEMBERS:
Presidente - 1356402 - CAROLINA LIPPARELLI MORELLI
Externa ao Programa - 3218488 - DAYANNE DINIZ DE SOUZA - nullInterno - 2215007 - FERNANDO HALLWASS