Banca de DEFESA: LARISSA KEROLLAINE MAIA GOMES

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : LARISSA KEROLLAINE MAIA GOMES
DATE: 24/07/2023
TIME: 14:00
LOCAL: Programa de Pós-Graduação em Ciência de Materiais
TITLE:

FIBERS OF PBAT WITH CINNAMON OIL PRODUCED BY SOLUTION BLOW SPINNING (SBS) - CHARACTERIZATION AND ANTIMICROBIAL STUDY.

KEY WORDS:

SBS; Nanofibers; PBAT; Cinnamomum cassia oil; Antimicrobial activity.

PAGES: 103
BIG AREA: Outra
AREA: Multidisciplinar
SUMMARY:

The Solution Blow Spinning (SBS) technique is a method that allows obtaining nonwoven mats of polymeric fibers that can be used in various biomedical applications such as scaffolds, dressings, and controlled drug release devices. Considering that cinnamon essential oil (C. Cassia) possesses antimicrobial properties, the aim of the present study was to develop poly(butylene adipate-co-terephthalate) (PBAT) nanofiber mats incorporated with cinnamon essential oil (CE) produced by SBS for their application in controlled release systems. The mats were produced from solutions containing 15% and 20% w/v PBAT in chloroform, and the effects of adding 20% mass of CE on the morphology and structural properties of the obtained mats were studied. The mats were characterized for their morphological properties (by SEM), thermal properties (by TGA and DSC), diffraction properties (by XRD), spectroscopic properties (by FTIR), and antimicrobial properties (by agar diffusion). SEM analysis revealed a cylindrical, smooth, and entangled morphology for all PBAT compositions, with fiber diameters ranging from an average of 242 to 314 nm for pure PBAT mats. After the addition of CE, these average diameters increased, ranging from 323 to 461 nm. CE acted as a plasticizer for PBAT, reducing its glass transition temperature (Tg), melting point (Tm), crystallization temperature (Tc), and crystallinity. XRD patterns of the mats showed that the incorporation of CE was not sufficient to induce any new phase formation in PBAT. FTIR results, with the aid of Principal Component Analysis (PCA), confirmed the presence of CE in the PBAT nanofibers. The nanofibers exhibited antimicrobial activity, with average inhibition zones ranging from 2.6 to 2.1 ± 0.1 mm for Escherichia coli and 1.4 to 1.6 ± 0.2 mm for Staphylococcus aureus.

COMMITTEE MEMBERS:
Interno - 1806089 - EDUARDO HENRIQUE LAGO FALCAO
Externo à Instituição - Eliton Souto de Medeiros - UFPB
Presidente - 1283002 - YEDA MEDEIROS BASTOS DE ALMEIDA