Banca de DEFESA: EMILIA BARBOSA GUIMARAES

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : EMILIA BARBOSA GUIMARAES
DATE: 31/08/2022
TIME: 09:00
LOCAL: Departamento de Histologia e Embriologia SH2
TITLE:

"Tannic Acid: Evaluation of Fluorescence, in vitro Skin Studies of Permeation and Photoprotective Effect"

KEY WORDS:

fotoprotetor, Permeação cutânea, Ácido tânico, Ácido Ascórbico, Óxido de Zinco.

PAGES: 15
BIG AREA: Ciências Biológicas
AREA: Morfologia
SUMMARY:

The incidence of damage such as skin cancer arising from ultraviolet radiation makes it important to investigate new photoprotectors accessible to all. This study evaluated the fluorescence, in vitro skin permeation and retention of tannic acid (TA) and the photoprotective effect in gel-cream. TA 5% in water was used to evaluate fluorescence and formulations 1 (cream-gel), 2 (TA 5% in water) and 3 (TA 5% in cream-gel) were used to evaluate permeation and retention into skin. Five different formulations were tested to photoprotective effect: Formulation A (TA 5% diluted in water (1:18)); Formulation B (Gel-cream base with TA 5%); Formulation C (Gel-cream base with physical filters); Formulation D (Gel-cream base with TA 5% and physical filters); Formulation E (TA 2.5% in gel-cream base and physical filters). TA was incorporated into gel-cream formulations evidencing auto-fluorescence, remaining retained to the epidermis showing an SPF of 26.4 with an adequate level of protection against UVB, considering its interactions with other compounds. The results suggest that TA can be used as a fluorescence probe and in products to protect and/or treat the most superficial layer of the skin, besides being a compound with potential UVB protection.

BANKING MEMBERS:
Presidente - 1859390 - JEYMESSON RAPHAEL CARDOSO VIEIRA
Interno - 2858463 - WHEVERTON RICARDO CORREIA DO NASCIMENTO
Externa ao Programa - 2313419 - LUCIANA MARIA SILVA DE SEIXAS MAIA
Externa à Instituição - DAYANE KELLY DIAS DO NASCIMENTO